Diagnosis & Therapy
Antibiotic therapy may alter the gut microbiota in a way that reduces the effectiveness of immune checkpoint inhibitors, according to a retrospective cohort study of patients with advanced renal cell carcinoma (RCC) or non–small cell lung cancer (NSCLC).read more
The trillions of microscopic organisms living in the gut and their ecosystem can alter how well immune checkpoint inhibitors work, for better or for worse.read more
More than 65,000 new cases of kidney cancer and almost 15,000 deaths are expected in 2018 in the United States, according to the American Cancer Society (ACS).read more
Experts in the treatment of renal cell carcinoma discussed the implications of the CARMENA trial in video and audio interviews conducted at the 2018 annual meeting of the American Society of Clinical Oncology in Chicago.read more
Kidney cancer has a number of known risk factors, but the connections between those risks and the disease are not so well known, according to the American Cancer Society.
Obesity is an important risk factor for renal cell carcinoma, the ACS notes on Cancer.org, while adding that it “may cause changes in certain hormones that can lead to RCC.” Gender also has an effect, with men twice as likely to develop RCC as women, but the ACS indicates that “men are more likely to be smokers and are more likely to be exposed to cancer-causing chemicals at work, which may account for some of the difference.”read more
Renal pathology is both a science and an art, requiring a breadth of knowledge about normal and abnormal tissues and a sharp, discerning eye that can detect patterns and features that can signal the presence and extent of malignancy.
Pathologists, with appropriate training and extensive experience, excel at analyzing complex visual patterns, but opinions about the gray areas – tissues with uncertain or borderline morphology – can differ and lead to different diagnostic conclusions.read more